Hypoxia-Induced Cardiopulmonary Remodeling and Recovery: Critical Roles of the Proximal Pulmonary Artery, Macrophages, and Exercise

A. Ramachandra, Prapti Sharma, R. De Man, Fadi Nikola, Nicole Guerrera, P. Doddaballapur, C. Cavinato, Rira Choi, M. Raredon, Jason M. Szafron, Zhuang W. Zhen, T. Barnthaler, Aurélien Justet, Ngozi D. Akingbesote, Nebal S. Abu Hussein, Lonnette Diggs, R. Perry, Taylor Sterling Adams, Inderjit Singh, N. Kaminski, Xiting Yan, G. Tellides, Jay D. Humphrey, Edward P. Manning

bioRxiv, 2025

Growth Arrest of Thoracic Aortic Aneurysms in Aging Marfan Mice

D. Weiss, Colin Means, Gavin Mays, N. Yeung, C. Cavinato, Edward P. Manning, Tukiet Lam, Jay D. Humphrey

bioRxiv, 2025

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

R. De Man, Zhongyu Cai, P. Doddaballapur, Nicole Guerrera, Liqin Lin, Aurélien Justet, Nebal S. Abu Hussein, C. Cavinato, M. Raredon, Paul Heerdt, Inderjit Singh, Xiting Yan, Min-Jong Kang, Danielle R. Bruns, Patty J. Lee, G. Tellides, Jay D. Humphrey, N. Kaminski, A. Ramachandra, Edward P. Manning

bioRxiv, 2025

A Systematic Comparison of Normal Structure and Function of the Greater Thoracic Vessels.

A. Ramachandra, C. Cavinato, J. Humphrey

Annals of Biomedical Engineering, 2024

AT1b receptors contribute to regional disparities in angiotensin II mediated aortic remodelling in mice

C. Cavinato, B. Spronck, Alexander W. Caulk, Sae-Il Murtada, J. Humphrey

Journal of the Royal Society Interface, 2024

Central Artery Hemodynamics in Angiotensin II-Induced Hypertension and Effects of Anesthesia.

S. Hopper, D. Weiss, N. Mikush, B. Jiang, B. Spronck, C. Cavinato, J. Humphrey, C. A. Figueroa

Annals of Biomedical Engineering, 2024

Computational modelling distinguishes diverse contributors to aneurysmal progression in the Marfan aorta

David S. Li, C. Cavinato, M. Latorre, J. Humphrey

Proceedings of the Royal Society A, 2023

Effects of Age, Sex, and Extracellular Matrix Integrity on Aortic Dilatation and Rupture in a Mouse Model of Marfan Syndrome

D. Weiss, B. Rego, C. Cavinato, David S. Li, Y. Kawamura, Nir Emuna, J. Humphrey

Arteriosclerosis, Thrombosis and Vascular Biology, 2023

Tempol improves aortic mechanics in a mouse model of hypertension.

J. A. Niestrawska, B. Spronck, C. Cavinato, J. Humphrey

Journal of Biomechanics, 2023

Persistent non-homeostatic remodeling of aortic collagen following a brief episode of hypertension: A computational study.

Linda Irons, C. Cavinato, J. Humphrey

Journal of The Mechanical Behavior of Biomedical Materials, 2023

A Generative Modeling Framework for Inferring Families of Biomechanical Constitutive Laws in Data-Sparse Regimes

Minglang Yin, Zongren Zou, Enrui Zhang, C. Cavinato, J. Humphrey, G. Karniadakis

Journal of the mechanics and physics of solids, 2023

Biomechanical and transcriptional evidence that smooth muscle cell death drives an osteochondrogenic phenotype and severe proximal vascular disease in progeria

Sae-Il Murtada, Y. Kawamura, C. Cavinato, Mo Wang, A. Ramachandra, B. Spronck, David S. Li, G. Tellides, J. Humphrey

Biomechanics and Modeling in Mechanobiology, 2023

Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria

Sae-Il Murtada, Y. Kawamura, C. Cavinato, Mo Wang, A. Ramachandra, B. Spronck, G. Tellides, J. Humphrey

bioRxiv, 2023

Predicting and understanding arterial elasticity from key microstructural features by bidirectional deep learning.

Kevin Linka, C. Cavinato, J. Humphrey, C. Cyron

Acta Biomaterialia, 2022

Predicting and Understanding Age-Dependent Arterial Elasticity from Key Microstructural Features by Bidirectional Deep Learning

K. Linka, C. Cavinato, J. Humphrey, C. Cyron

Social Science Research Network, 2022

Fibronectin-integrin α5 signaling in vascular complications of type 1 diabetes.

Minghao Chen, Rui Hu, C. Cavinato, Z. Zhuang, Jiasheng Zhang, Sanguk Yun, P. F. Tussy, Abhishek K. Singh, Sae-Il Murtada, Keiichiro Tanaka, Min Liu, C. Fernández-Hernando, J. Humphrey, Martin A. Schwartz

Diabetes, 2022

Abstract P236: Role Of Axl In Target Organ Inflammation And Damage Due To Hypertensive Aortic Remodeling

Wei Chen, Justin P. Van Beusecum, Liang Xiao, David M. Patrick, Mingfang Ao, Shilin Zhao, C. Cavinato, Alexander W. Caulk, Jay D. Humphrey, David G. Harrison

HYPERTENSION, 2022

Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling.

Wei Chen, Justin P. Van Beusecum, Liang Xiao, D. Patrick, Mingfang Ao, Shilin Zhao, Marcos G. Lopez, F. Billings, C. Cavinato, Alexander W. Caulk, J. Humphrey, David G. Harrison

American Journal of Physiology. Heart and Circulatory Physiology, 2022

Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta

C. Cavinato, Minghao Chen, D. Weiss, M. J. Ruíz-Rodríguez, Martin A. Schwartz, J. Humphrey

Frontiers in Cardiovascular Medicine, 2021

Evolving structure-function relations during aortic maturation and aging revealed by multiphoton microscopy

C. Cavinato, Sae-Il Murtada, Alexia Rojas, J. Humphrey

Mechanisms of Ageing and Development, 2021

Critical Pressure of Intramural Delamination in Aortic Dissection

Ehsan Ban, C. Cavinato, J. Humphrey

Annals of Biomedical Engineering, 2021

Differential propensity of dissection along the aorta

Ehsan Ban, C. Cavinato, J. Humphrey

Biomechanics and Modeling in Mechanobiology, 2021

Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data

E. Manning, A. Ramachandra, J. Schupp, C. Cavinato, M. Raredon, T. Bärnthaler, C. Cosme, I. Singh, G. Tellides, N. Kaminski, J. Humphrey

Frontiers in Physiology, 2021

Multi-view Digital Image Correlation Systems for In Vitro Testing of Arteries from Mice to Humans

K. Genovese, P. Badel, C. Cavinato, B. Pierrat, M. Bersi, S. Avril, J. Humphrey

Experimental mechanics, 2021

Simulating progressive intramural damage leading to aortic dissection using DeepONet: an operator–regression neural network

Minglang Yin, Ehsan Ban, B. Rego, Enrui Zhang, C. Cavinato, J. Humphrey, G. Em Karniadakis

Journal of the Royal Society Interface, 2021

P.20 Evolving Structure-Function Correlates during Aortic Maturation and Aging

C. Cavinato, J. Humphrey

Artery Research, 2020

Mechanics-driven mechanobiological mechanisms of arterial tortuosity

D. Weiss, C. Cavinato, Authia Gray, A. Ramachandra, S. Avril, J. Humphrey, M. Latorre

Science Advances, 2020

Characterization of deformation and rupture micro-méchanisms in aortic aneurysm wall.

C. Cavinato

2019

Does the Knowledge of the Local Thickness of Human Ascending Thoracic Aneurysm Walls Improve Their Mechanical Analysis?

C. Cavinato, J. Molimard, N. Curt, S. Campisi, Laurent Orgéas, P. Badel

Frontiers in Bioengineering and Biotechnology, 2019

Experimental characterization of aneurysmal aortic tissue rupture under bulge inflation loading in a confocal microscope

C. Cavinato, Laurent Orgéas, S. R. Roscoat, S. Campisi, P. Badel, J. Monnet

2019

Experimental Characterization of Adventitial Collagen Fiber Kinematics Using Second-Harmonic Generation Imaging Microscopy: Similarities and Differences Across Arteries, Species and Testing Conditions

C. Cavinato, P. Badel, W. Krasny, S. Avril, C. Morin

Multi-scale Extracellular Matrix Mechanics and Mechanobiology, 2019

Biaxial loading of arterial tissues with 3D in situ observations of adventitia fibrous microstructure: A method coupling multi-photon confocal microscopy and bulge inflation test.

C. Cavinato, C. Helfenstein-Didier, T. Olivier, S. R. Du Roscoat, N. Laroche, P. Badel

Journal of The Mechanical Behavior of Biomedical Materials, 2017

Fluid- and Biomechanical Analysis of Ascending Thoracic Aorta Aneurysm with Concomitant Aortic Insufficiency

F. Condemi, F. Condemi, F. Condemi, Salvatore Campisi, M. Viallon, Thomas Troalen, G. Xuexin, A. Barker, M. Markl, P. Croisille, O. Trabelsi, O. Trabelsi, O. Trabelsi, Cristina Cavinato, Cristina Cavinato, Cristina Cavinato, A. Duprey, Stephane Avril, Stephane Avril, Stephane Avril

Annals of Biomedical Engineering, 2017

A numerical investigation of the healthy abdominal wall structures.

Paola Pachera, P. Pavan, S. Todros, C. Cavinato, C. Fontanella, A. Natali

Journal of Biomechanics, 2016

Hypoxia-Induced Cardiopulmonary Remodeling and Recovery: Critical Roles of the Proximal Pulmonary Artery, Macrophages, and Exercise

A. Ramachandra, Prapti Sharma, R. De Man, Fadi Nikola, Nicole Guerrera, P. Doddaballapur, C. Cavinato, Rira Choi, M. Raredon, Jason M. Szafron, Zhuang W. Zhen, T. Barnthaler, Aurélien Justet, Ngozi D. Akingbesote, Nebal S. Abu Hussein, Lonnette Diggs, R. Perry, Taylor Sterling Adams, Inderjit Singh, N. Kaminski, Xiting Yan, G. Tellides, Jay D. Humphrey, Edward P. Manning

bioRxiv, 2025

Growth Arrest of Thoracic Aortic Aneurysms in Aging Marfan Mice

D. Weiss, Colin Means, Gavin Mays, N. Yeung, C. Cavinato, Edward P. Manning, Tukiet Lam, Jay D. Humphrey

bioRxiv, 2025

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

R. De Man, Zhongyu Cai, P. Doddaballapur, Nicole Guerrera, Liqin Lin, Aurélien Justet, Nebal S. Abu Hussein, C. Cavinato, M. Raredon, Paul Heerdt, Inderjit Singh, Xiting Yan, Min-Jong Kang, Danielle R. Bruns, Patty J. Lee, G. Tellides, Jay D. Humphrey, N. Kaminski, A. Ramachandra, Edward P. Manning

bioRxiv, 2025

A Systematic Comparison of Normal Structure and Function of the Greater Thoracic Vessels.

A. Ramachandra, C. Cavinato, J. Humphrey

Annals of Biomedical Engineering, 2024

AT1b receptors contribute to regional disparities in angiotensin II mediated aortic remodelling in mice

C. Cavinato, B. Spronck, Alexander W. Caulk, Sae-Il Murtada, J. Humphrey

Journal of the Royal Society Interface, 2024

Central Artery Hemodynamics in Angiotensin II-Induced Hypertension and Effects of Anesthesia.

S. Hopper, D. Weiss, N. Mikush, B. Jiang, B. Spronck, C. Cavinato, J. Humphrey, C. A. Figueroa

Annals of Biomedical Engineering, 2024

Computational modelling distinguishes diverse contributors to aneurysmal progression in the Marfan aorta

David S. Li, C. Cavinato, M. Latorre, J. Humphrey

Proceedings of the Royal Society A, 2023

Effects of Age, Sex, and Extracellular Matrix Integrity on Aortic Dilatation and Rupture in a Mouse Model of Marfan Syndrome

D. Weiss, B. Rego, C. Cavinato, David S. Li, Y. Kawamura, Nir Emuna, J. Humphrey

Arteriosclerosis, Thrombosis and Vascular Biology, 2023

Tempol improves aortic mechanics in a mouse model of hypertension.

J. A. Niestrawska, B. Spronck, C. Cavinato, J. Humphrey

Journal of Biomechanics, 2023

Persistent non-homeostatic remodeling of aortic collagen following a brief episode of hypertension: A computational study.

Linda Irons, C. Cavinato, J. Humphrey

Journal of The Mechanical Behavior of Biomedical Materials, 2023

A Generative Modeling Framework for Inferring Families of Biomechanical Constitutive Laws in Data-Sparse Regimes

Minglang Yin, Zongren Zou, Enrui Zhang, C. Cavinato, J. Humphrey, G. Karniadakis

Journal of the mechanics and physics of solids, 2023

Biomechanical and transcriptional evidence that smooth muscle cell death drives an osteochondrogenic phenotype and severe proximal vascular disease in progeria

Sae-Il Murtada, Y. Kawamura, C. Cavinato, Mo Wang, A. Ramachandra, B. Spronck, David S. Li, G. Tellides, J. Humphrey

Biomechanics and Modeling in Mechanobiology, 2023

Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria

Sae-Il Murtada, Y. Kawamura, C. Cavinato, Mo Wang, A. Ramachandra, B. Spronck, G. Tellides, J. Humphrey

bioRxiv, 2023

Predicting and understanding arterial elasticity from key microstructural features by bidirectional deep learning.

Kevin Linka, C. Cavinato, J. Humphrey, C. Cyron

Acta Biomaterialia, 2022

Predicting and Understanding Age-Dependent Arterial Elasticity from Key Microstructural Features by Bidirectional Deep Learning

K. Linka, C. Cavinato, J. Humphrey, C. Cyron

Social Science Research Network, 2022

Fibronectin-integrin α5 signaling in vascular complications of type 1 diabetes.

Minghao Chen, Rui Hu, C. Cavinato, Z. Zhuang, Jiasheng Zhang, Sanguk Yun, P. F. Tussy, Abhishek K. Singh, Sae-Il Murtada, Keiichiro Tanaka, Min Liu, C. Fernández-Hernando, J. Humphrey, Martin A. Schwartz

Diabetes, 2022

Abstract P236: Role Of Axl In Target Organ Inflammation And Damage Due To Hypertensive Aortic Remodeling

Wei Chen, Justin P. Van Beusecum, Liang Xiao, David M. Patrick, Mingfang Ao, Shilin Zhao, C. Cavinato, Alexander W. Caulk, Jay D. Humphrey, David G. Harrison

HYPERTENSION, 2022

Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling.

Wei Chen, Justin P. Van Beusecum, Liang Xiao, D. Patrick, Mingfang Ao, Shilin Zhao, Marcos G. Lopez, F. Billings, C. Cavinato, Alexander W. Caulk, J. Humphrey, David G. Harrison

American Journal of Physiology. Heart and Circulatory Physiology, 2022

Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta

C. Cavinato, Minghao Chen, D. Weiss, M. J. Ruíz-Rodríguez, Martin A. Schwartz, J. Humphrey

Frontiers in Cardiovascular Medicine, 2021

Evolving structure-function relations during aortic maturation and aging revealed by multiphoton microscopy

C. Cavinato, Sae-Il Murtada, Alexia Rojas, J. Humphrey

Mechanisms of Ageing and Development, 2021

Critical Pressure of Intramural Delamination in Aortic Dissection

Ehsan Ban, C. Cavinato, J. Humphrey

Annals of Biomedical Engineering, 2021

Differential propensity of dissection along the aorta

Ehsan Ban, C. Cavinato, J. Humphrey

Biomechanics and Modeling in Mechanobiology, 2021

Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data

E. Manning, A. Ramachandra, J. Schupp, C. Cavinato, M. Raredon, T. Bärnthaler, C. Cosme, I. Singh, G. Tellides, N. Kaminski, J. Humphrey

Frontiers in Physiology, 2021

Multi-view Digital Image Correlation Systems for In Vitro Testing of Arteries from Mice to Humans

K. Genovese, P. Badel, C. Cavinato, B. Pierrat, M. Bersi, S. Avril, J. Humphrey

Experimental mechanics, 2021

Simulating progressive intramural damage leading to aortic dissection using DeepONet: an operator–regression neural network

Minglang Yin, Ehsan Ban, B. Rego, Enrui Zhang, C. Cavinato, J. Humphrey, G. Em Karniadakis

Journal of the Royal Society Interface, 2021

P.20 Evolving Structure-Function Correlates during Aortic Maturation and Aging

C. Cavinato, J. Humphrey

Artery Research, 2020

Mechanics-driven mechanobiological mechanisms of arterial tortuosity

D. Weiss, C. Cavinato, Authia Gray, A. Ramachandra, S. Avril, J. Humphrey, M. Latorre

Science Advances, 2020

Characterization of deformation and rupture micro-méchanisms in aortic aneurysm wall.

C. Cavinato

2019

Does the Knowledge of the Local Thickness of Human Ascending Thoracic Aneurysm Walls Improve Their Mechanical Analysis?

C. Cavinato, J. Molimard, N. Curt, S. Campisi, Laurent Orgéas, P. Badel

Frontiers in Bioengineering and Biotechnology, 2019

Experimental characterization of aneurysmal aortic tissue rupture under bulge inflation loading in a confocal microscope

C. Cavinato, Laurent Orgéas, S. R. Roscoat, S. Campisi, P. Badel, J. Monnet

2019

Experimental Characterization of Adventitial Collagen Fiber Kinematics Using Second-Harmonic Generation Imaging Microscopy: Similarities and Differences Across Arteries, Species and Testing Conditions

C. Cavinato, P. Badel, W. Krasny, S. Avril, C. Morin

Multi-scale Extracellular Matrix Mechanics and Mechanobiology, 2019

Biaxial loading of arterial tissues with 3D in situ observations of adventitia fibrous microstructure: A method coupling multi-photon confocal microscopy and bulge inflation test.

C. Cavinato, C. Helfenstein-Didier, T. Olivier, S. R. Du Roscoat, N. Laroche, P. Badel

Journal of The Mechanical Behavior of Biomedical Materials, 2017

Fluid- and Biomechanical Analysis of Ascending Thoracic Aorta Aneurysm with Concomitant Aortic Insufficiency

F. Condemi, F. Condemi, F. Condemi, Salvatore Campisi, M. Viallon, Thomas Troalen, G. Xuexin, A. Barker, M. Markl, P. Croisille, O. Trabelsi, O. Trabelsi, O. Trabelsi, Cristina Cavinato, Cristina Cavinato, Cristina Cavinato, A. Duprey, Stephane Avril, Stephane Avril, Stephane Avril

Annals of Biomedical Engineering, 2017

A numerical investigation of the healthy abdominal wall structures.

Paola Pachera, P. Pavan, S. Todros, C. Cavinato, C. Fontanella, A. Natali

Journal of Biomechanics, 2016

Hypoxia-Induced Cardiopulmonary Remodeling and Recovery: Critical Roles of the Proximal Pulmonary Artery, Macrophages, and Exercise

A. Ramachandra, Prapti Sharma, R. De Man, Fadi Nikola, Nicole Guerrera, P. Doddaballapur, C. Cavinato, Rira Choi, M. Raredon, Jason M. Szafron, Zhuang W. Zhen, T. Barnthaler, Aurélien Justet, Ngozi D. Akingbesote, Nebal S. Abu Hussein, Lonnette Diggs, R. Perry, Taylor Sterling Adams, Inderjit Singh, N. Kaminski, Xiting Yan, G. Tellides, Jay D. Humphrey, Edward P. Manning

bioRxiv, 2025

Growth Arrest of Thoracic Aortic Aneurysms in Aging Marfan Mice

D. Weiss, Colin Means, Gavin Mays, N. Yeung, C. Cavinato, Edward P. Manning, Tukiet Lam, Jay D. Humphrey

bioRxiv, 2025

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

R. De Man, Zhongyu Cai, P. Doddaballapur, Nicole Guerrera, Liqin Lin, Aurélien Justet, Nebal S. Abu Hussein, C. Cavinato, M. Raredon, Paul Heerdt, Inderjit Singh, Xiting Yan, Min-Jong Kang, Danielle R. Bruns, Patty J. Lee, G. Tellides, Jay D. Humphrey, N. Kaminski, A. Ramachandra, Edward P. Manning

bioRxiv, 2025

A Systematic Comparison of Normal Structure and Function of the Greater Thoracic Vessels.

A. Ramachandra, C. Cavinato, J. Humphrey

Annals of Biomedical Engineering, 2024

AT1b receptors contribute to regional disparities in angiotensin II mediated aortic remodelling in mice

C. Cavinato, B. Spronck, Alexander W. Caulk, Sae-Il Murtada, J. Humphrey

Journal of the Royal Society Interface, 2024

Central Artery Hemodynamics in Angiotensin II-Induced Hypertension and Effects of Anesthesia.

S. Hopper, D. Weiss, N. Mikush, B. Jiang, B. Spronck, C. Cavinato, J. Humphrey, C. A. Figueroa

Annals of Biomedical Engineering, 2024

Computational modelling distinguishes diverse contributors to aneurysmal progression in the Marfan aorta

David S. Li, C. Cavinato, M. Latorre, J. Humphrey

Proceedings of the Royal Society A, 2023

Effects of Age, Sex, and Extracellular Matrix Integrity on Aortic Dilatation and Rupture in a Mouse Model of Marfan Syndrome

D. Weiss, B. Rego, C. Cavinato, David S. Li, Y. Kawamura, Nir Emuna, J. Humphrey

Arteriosclerosis, Thrombosis and Vascular Biology, 2023

Tempol improves aortic mechanics in a mouse model of hypertension.

J. A. Niestrawska, B. Spronck, C. Cavinato, J. Humphrey

Journal of Biomechanics, 2023

Persistent non-homeostatic remodeling of aortic collagen following a brief episode of hypertension: A computational study.

Linda Irons, C. Cavinato, J. Humphrey

Journal of The Mechanical Behavior of Biomedical Materials, 2023

A Generative Modeling Framework for Inferring Families of Biomechanical Constitutive Laws in Data-Sparse Regimes

Minglang Yin, Zongren Zou, Enrui Zhang, C. Cavinato, J. Humphrey, G. Karniadakis

Journal of the mechanics and physics of solids, 2023

Biomechanical and transcriptional evidence that smooth muscle cell death drives an osteochondrogenic phenotype and severe proximal vascular disease in progeria

Sae-Il Murtada, Y. Kawamura, C. Cavinato, Mo Wang, A. Ramachandra, B. Spronck, David S. Li, G. Tellides, J. Humphrey

Biomechanics and Modeling in Mechanobiology, 2023

Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria

Sae-Il Murtada, Y. Kawamura, C. Cavinato, Mo Wang, A. Ramachandra, B. Spronck, G. Tellides, J. Humphrey

bioRxiv, 2023

Predicting and understanding arterial elasticity from key microstructural features by bidirectional deep learning.

Kevin Linka, C. Cavinato, J. Humphrey, C. Cyron

Acta Biomaterialia, 2022

Predicting and Understanding Age-Dependent Arterial Elasticity from Key Microstructural Features by Bidirectional Deep Learning

K. Linka, C. Cavinato, J. Humphrey, C. Cyron

Social Science Research Network, 2022

Fibronectin-integrin α5 signaling in vascular complications of type 1 diabetes.

Minghao Chen, Rui Hu, C. Cavinato, Z. Zhuang, Jiasheng Zhang, Sanguk Yun, P. F. Tussy, Abhishek K. Singh, Sae-Il Murtada, Keiichiro Tanaka, Min Liu, C. Fernández-Hernando, J. Humphrey, Martin A. Schwartz

Diabetes, 2022

Abstract P236: Role Of Axl In Target Organ Inflammation And Damage Due To Hypertensive Aortic Remodeling

Wei Chen, Justin P. Van Beusecum, Liang Xiao, David M. Patrick, Mingfang Ao, Shilin Zhao, C. Cavinato, Alexander W. Caulk, Jay D. Humphrey, David G. Harrison

HYPERTENSION, 2022

Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling.

Wei Chen, Justin P. Van Beusecum, Liang Xiao, D. Patrick, Mingfang Ao, Shilin Zhao, Marcos G. Lopez, F. Billings, C. Cavinato, Alexander W. Caulk, J. Humphrey, David G. Harrison

American Journal of Physiology. Heart and Circulatory Physiology, 2022

Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta

C. Cavinato, Minghao Chen, D. Weiss, M. J. Ruíz-Rodríguez, Martin A. Schwartz, J. Humphrey

Frontiers in Cardiovascular Medicine, 2021

Evolving structure-function relations during aortic maturation and aging revealed by multiphoton microscopy

C. Cavinato, Sae-Il Murtada, Alexia Rojas, J. Humphrey

Mechanisms of Ageing and Development, 2021

Critical Pressure of Intramural Delamination in Aortic Dissection

Ehsan Ban, C. Cavinato, J. Humphrey

Annals of Biomedical Engineering, 2021

Differential propensity of dissection along the aorta

Ehsan Ban, C. Cavinato, J. Humphrey

Biomechanics and Modeling in Mechanobiology, 2021

Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data

E. Manning, A. Ramachandra, J. Schupp, C. Cavinato, M. Raredon, T. Bärnthaler, C. Cosme, I. Singh, G. Tellides, N. Kaminski, J. Humphrey

Frontiers in Physiology, 2021

Multi-view Digital Image Correlation Systems for In Vitro Testing of Arteries from Mice to Humans

K. Genovese, P. Badel, C. Cavinato, B. Pierrat, M. Bersi, S. Avril, J. Humphrey

Experimental mechanics, 2021

Simulating progressive intramural damage leading to aortic dissection using DeepONet: an operator–regression neural network

Minglang Yin, Ehsan Ban, B. Rego, Enrui Zhang, C. Cavinato, J. Humphrey, G. Em Karniadakis

Journal of the Royal Society Interface, 2021

P.20 Evolving Structure-Function Correlates during Aortic Maturation and Aging

C. Cavinato, J. Humphrey

Artery Research, 2020

Mechanics-driven mechanobiological mechanisms of arterial tortuosity

D. Weiss, C. Cavinato, Authia Gray, A. Ramachandra, S. Avril, J. Humphrey, M. Latorre

Science Advances, 2020

Characterization of deformation and rupture micro-méchanisms in aortic aneurysm wall.

C. Cavinato

2019

Does the Knowledge of the Local Thickness of Human Ascending Thoracic Aneurysm Walls Improve Their Mechanical Analysis?

C. Cavinato, J. Molimard, N. Curt, S. Campisi, Laurent Orgéas, P. Badel

Frontiers in Bioengineering and Biotechnology, 2019

Experimental characterization of aneurysmal aortic tissue rupture under bulge inflation loading in a confocal microscope

C. Cavinato, Laurent Orgéas, S. R. Roscoat, S. Campisi, P. Badel, J. Monnet

2019

Experimental Characterization of Adventitial Collagen Fiber Kinematics Using Second-Harmonic Generation Imaging Microscopy: Similarities and Differences Across Arteries, Species and Testing Conditions

C. Cavinato, P. Badel, W. Krasny, S. Avril, C. Morin

Multi-scale Extracellular Matrix Mechanics and Mechanobiology, 2019

Biaxial loading of arterial tissues with 3D in situ observations of adventitia fibrous microstructure: A method coupling multi-photon confocal microscopy and bulge inflation test.

C. Cavinato, C. Helfenstein-Didier, T. Olivier, S. R. Du Roscoat, N. Laroche, P. Badel

Journal of The Mechanical Behavior of Biomedical Materials, 2017

Fluid- and Biomechanical Analysis of Ascending Thoracic Aorta Aneurysm with Concomitant Aortic Insufficiency

F. Condemi, F. Condemi, F. Condemi, Salvatore Campisi, M. Viallon, Thomas Troalen, G. Xuexin, A. Barker, M. Markl, P. Croisille, O. Trabelsi, O. Trabelsi, O. Trabelsi, Cristina Cavinato, Cristina Cavinato, Cristina Cavinato, A. Duprey, Stephane Avril, Stephane Avril, Stephane Avril

Annals of Biomedical Engineering, 2017

A numerical investigation of the healthy abdominal wall structures.

Paola Pachera, P. Pavan, S. Todros, C. Cavinato, C. Fontanella, A. Natali

Journal of Biomechanics, 2016